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Ishan Goyal

Business Development & Product Operations

Operator with 8 years of zero to one product building experience in deep-tech industries such as blockchain & biotechnology. Most recently leading business development for Coinbase's Base blockchain.

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Work Experience

Coinbase (Base)

Infrastructure Lead, Business & Corporate Development

Oct 2024 — Present
  • Negotiate a stablecoin checkout deal with Shopify expected to process $600M in gross merchandise value
  • Select infrastructure providers to serve blockchain and social graph data to Coinbase Wallet
  • Reduce block times on Base from 2 seconds to 200 milliseconds through Flashbots block building primitives
  • Launch Base Appchains SaaS product to 10 gaming and decentralized physical infrastructure network customers
  • Serve as single point of contact for 150+ teams building developer tooling on Base

Orange DAO

Head of Ecosystem & Senior Venture Partner

Jan 2023 — Present
  • Led investments in Neynar, Privy (acquired by Stripe), Sapien, ZeroDev (acquired by Offchain Labs)
  • Closed $30M USD from layer-one blockchain partnerships with Algorand, Filecoin & Near Protocol
  • Built real-world asset yield strategies backed by private credit lending in emerging markets
  • Secured $15M in deposits from market makers & proprietary trading firms

Epinoma Inc.

Co-founder & Chief Operating Officer

Jun 2020 — Dec 2022
  • Oversaw product development from research publication to commercial assay (exited to ACT Genomics)
  • Led sales pipeline with 30+ diagnostic & pharmaceutical companies resulting in $1M ARR
  • Conducted 200+ customer interviews to validate value proposition and secure letters of intent

Genentech Inc.

Business Operations & Process Development

Jun 2018 — May 2021
  • Supported $60B pharmaceutical portfolio by collaborating with CMO to optimize R&D investment decisions
  • Created business analytics dashboards to measure utility of oncology datasets across 350 ongoing clinical trials
  • Built a product development framework for new precision medicine technologies
  • Developed a full-stack web application saving the equivalent of 3 full-time employees per year

About Me

Hi, I'm Ishan Goyal, an operator with 8 years of zero to one product building experience, specifically in deep-tech industries such as blockchain and biotechnology. I'm currently leading business development for Coinbase's layer-two blockchain, Base, where I've helped double the assets on platform to $15B and negotiated major enterprise deals including a stablecoin checkout integration with Shopify across 2 million merchants. My background spans from co-founding Epinoma, a biotech company developing novel DNA methylation-based diagnostics, to working at Genentech on a $60B pharmaceutical portfolio. I'm a Y Combinator alum and have published research in Nature Cell Biology. My highly technical background coupled with my ability to refine the voice of customer allows me to navigate and successfully close complex partnerships in emerging technology sectors. Based in San Francisco, I'm passionate about building products that push the boundaries of what's possible in deep-tech industries.

Ishan Goyal